K9 Advantix II for Dogs
K9 Advantix II is a topical spot-on known for combining fast flea kill with tick repellency, making it a strong choice for dogs that spend a lot of time outdoors. In a subscription model it competes on broad external parasite coverage and typically sits in the mid-price range; compared with Advantage II it adds tick protection, and compared with long-acting Bravecto it requires monthly dosing but offers repellent activity that some owners prefer.
Repels mosquitoes
Kills fleas fast
Repels mosquitoes
Kills fleas fast
Review Summary
"Users generally praise K9 Advantix II for strong month-to-month flea and tick repellent action and easy topical application; some report mild skin irritation in sensitive dogs and caution that the product is toxic to cats. Overall reliability is good for most households but not universal in heavy-infestation areas."
Swim-safe swagger
Monthly topical with imidacloprid + permethrin delivering rapid flea knockdown and tick-repellent action.
Swim-safe swagger
Monthly topical with imidacloprid + permethrin delivering rapid flea knockdown and tick-repellent action.
Increased Safety & Security
Time-Saving Convenience
K9 Advantix II is a topical spot-on known for combining fast flea kill with tick repellency, making it a strong choice for dogs that spend a lot of time outdoors. In a subscription model it competes on broad external parasite coverage and typically sits in the mid-price range; compared with Advantage II it adds tick protection, and compared with long-acting Bravecto it requires monthly dosing but offers repellent activity that some owners prefer.
Repels mosquitoes
Kills fleas fast
Swim-safe swagger
Monthly topical with imidacloprid + permethrin delivering rapid flea knockdown and tick-repellent action.
Water-resistant after application and effective against common American tick species.
Repels mosquitoes
Kills fleas fast
Swim-safe swagger
Monthly topical with imidacloprid + permethrin delivering rapid flea knockdown and tick-repellent action.
Water-resistant after application and effective against common American tick species.
$200-320 USD
Frontline Plus for Dogs
Frontline Plus is a long-established monthly topical treatment with a proven track record for killing fleas and ticks and breaking the flea life cycle. As a subscription product it offers dependable residual control and broad retail availability; technically it is less of a repellent than K9 Advantix II and does not offer the multi-parasite systemic coverage of Revolution Plus, but it is often positioned as a reliable, mid-tier solution with consistent efficacy.
Proven flea killer
Breaks flea lifecycle
Proven flea killer
Breaks flea lifecycle
Review Summary
"Frontline Plus is a long-standing favorite for consistent flea control with many long-term users reporting satisfactory results; however, some owners note diminished tick performance and occasional treatment failures in high-pressure areas. Many appreciate its proven track record despite rising reports of resistance in some regions."
Vet-trusted badge
Contains fipronil and (S)-methoprene to kill adult fleas and interrupt the flea life cycle by targeting eggs and larvae.
Vet-trusted badge
Contains fipronil and (S)-methoprene to kill adult fleas and interrupt the flea life cycle by targeting eggs and larvae.
Increased Safety & Security
Time-Saving Convenience
Frontline Plus is a long-established monthly topical treatment with a proven track record for killing fleas and ticks and breaking the flea life cycle. As a subscription product it offers dependable residual control and broad retail availability; technically it is less of a repellent than K9 Advantix II and does not offer the multi-parasite systemic coverage of Revolution Plus, but it is often positioned as a reliable, mid-tier solution with consistent efficacy.
Proven flea killer
Breaks flea lifecycle
Vet-trusted badge
Contains fipronil and (S)-methoprene to kill adult fleas and interrupt the flea life cycle by targeting eggs and larvae.
Monthly topical with a long track record and broad availability through veterinarians and subscription services.
Proven flea killer
Breaks flea lifecycle
Vet-trusted badge
Contains fipronil and (S)-methoprene to kill adult fleas and interrupt the flea life cycle by targeting eggs and larvae.
Monthly topical with a long track record and broad availability through veterinarians and subscription services.
$220-380 USD
Advantage II for Dogs
Advantage II is a monthly topical optimized specifically for rapid flea elimination and prevention, delivering strong value for dogs whose primary risk is fleas rather than ticks. Financially it is frequently priced lower than combined flea-and-tick products and is a sensible subscription choice for flea-focused control; however, it lacks tick activity found in K9 Advantix II, Frontline Plus, Revolution Plus, and Bravecto, so it is less comprehensive where tick exposure is a concern.
Flea lifecycle breaker
Gentle on skin
Flea lifecycle breaker
Gentle on skin
Review Summary
"Advantage II is widely admired for fast, reliable flea killing and breaking reinfestation cycles, but users who need tick protection are disappointed since it does not cover ticks. It’s often recommended for indoor pets or those in mainly flea-prone environments."
Puddle-proof perk
Imidacloprid + pyriproxyfen monthly topical formulated primarily to kill fleas and prevent egg development.
Puddle-proof perk
Imidacloprid + pyriproxyfen monthly topical formulated primarily to kill fleas and prevent egg development.
Increased Safety & Security
Time-Saving Convenience
Advantage II is a monthly topical optimized specifically for rapid flea elimination and prevention, delivering strong value for dogs whose primary risk is fleas rather than ticks. Financially it is frequently priced lower than combined flea-and-tick products and is a sensible subscription choice for flea-focused control; however, it lacks tick activity found in K9 Advantix II, Frontline Plus, Revolution Plus, and Bravecto, so it is less comprehensive where tick exposure is a concern.
Flea lifecycle breaker
Gentle on skin
Puddle-proof perk
Imidacloprid + pyriproxyfen monthly topical formulated primarily to kill fleas and prevent egg development.
Fast-acting against heavy flea infestations and effective at breaking the flea life cycle.
Flea lifecycle breaker
Gentle on skin
Puddle-proof perk
Imidacloprid + pyriproxyfen monthly topical formulated primarily to kill fleas and prevent egg development.
Fast-acting against heavy flea infestations and effective at breaking the flea life cycle.
$180-270 USD
Revolution Plus for Dogs
Revolution Plus is a monthly topical systemic that protects against fleas, ticks, mites and certain internal parasites (including heartworm), giving it the broadest parasite coverage among spot-on options in this list. For subscription buyers it can replace multiple separate products—offering technical and potential cost advantages by consolidating parasite control—though it differs from repellent products by relying on systemic action and requires monthly adherence compared with Bravecto's longer dosing interval.
Broad-spectrum defense
Prevents heartworm too
Broad-spectrum defense
Prevents heartworm too
Review Summary
"Revolution Plus receives strong praise for broad-spectrum protection (fleas, ticks, heartworm, mites) and dependable monthly coverage, with many users valuing the expanded parasite protection despite higher cost; a minority report mild side effects. Overall satisfaction is high among owners seeking all-in-one prevention."
One-drop superhero
Combines selamectin and sarolaner for monthly protection against fleas, ticks, and additional parasites like certain intestinal worms and ear mites.
One-drop superhero
Combines selamectin and sarolaner for monthly protection against fleas, ticks, and additional parasites like certain intestinal worms and ear mites.
Increased Safety & Security
Time-Saving Convenience
Revolution Plus is a monthly topical systemic that protects against fleas, ticks, mites and certain internal parasites (including heartworm), giving it the broadest parasite coverage among spot-on options in this list. For subscription buyers it can replace multiple separate products—offering technical and potential cost advantages by consolidating parasite control—though it differs from repellent products by relying on systemic action and requires monthly adherence compared with Bravecto's longer dosing interval.
Broad-spectrum defense
Prevents heartworm too
One-drop superhero
Combines selamectin and sarolaner for monthly protection against fleas, ticks, and additional parasites like certain intestinal worms and ear mites.
Veterinary-prescription product favored when multi-parasite coverage is desired in one subscription.
Broad-spectrum defense
Prevents heartworm too
One-drop superhero
Combines selamectin and sarolaner for monthly protection against fleas, ticks, and additional parasites like certain intestinal worms and ear mites.
Veterinary-prescription product favored when multi-parasite coverage is desired in one subscription.
$320-480 USD
Bravecto Topical Solution for Dogs
Bravecto topical uses a long-acting active ingredient that provides up to 12 weeks of flea and tick protection per dose, which substantially reduces dosing frequency and can lower overall subscription administration burden. It is often viewed as the most cost-effective option on a per-month basis for owners prioritizing fewer doses; however, unlike Revolution Plus it does not provide heartworm or broader internal parasite prevention, and unlike K9 Advantix II it is not marketed for repellency.
12-week protection
Fast flea knockdown
12-week protection
Fast flea knockdown
Review Summary
"Bravecto Topical is lauded for its long-lasting 12-week efficacy against fleas and ticks and convenience of fewer doses, with most users reporting excellent control; a small percentage report adverse reactions or variable results in certain circumstances. Many prefer it for the extended protection interval."
Quarterly freedom
Fluralaner topical providing up to 12 weeks of protection per dose against fleas and ticks, reducing application frequency.
Quarterly freedom
Fluralaner topical providing up to 12 weeks of protection per dose against fleas and ticks, reducing application frequency.
Time-Saving Convenience
Increased Safety & Security
Bravecto topical uses a long-acting active ingredient that provides up to 12 weeks of flea and tick protection per dose, which substantially reduces dosing frequency and can lower overall subscription administration burden. It is often viewed as the most cost-effective option on a per-month basis for owners prioritizing fewer doses; however, unlike Revolution Plus it does not provide heartworm or broader internal parasite prevention, and unlike K9 Advantix II it is not marketed for repellency.
12-week protection
Fast flea knockdown
Quarterly freedom
Fluralaner topical providing up to 12 weeks of protection per dose against fleas and ticks, reducing application frequency.
Highly effective against many tick species and convenient for owners preferring quarterly dosing schedules.
12-week protection
Fast flea knockdown
Quarterly freedom
Fluralaner topical providing up to 12 weeks of protection per dose against fleas and ticks, reducing application frequency.
Highly effective against many tick species and convenient for owners preferring quarterly dosing schedules.
$260-420 USD