NexGard Chewables
NexGard is a monthly afoxolaner oral chewable widely used for reliable flea and tick control; its large market share and competitive monthly price make it a practical core option for subscription services. Compared with longer-acting alternatives like Bravecto, NexGard’s monthly cadence yields predictable recurring revenue and simpler dose adjustments, and its narrower scope can be a lower-cost choice versus combination products that bundle heartworm or intestinal parasite protection.
Beef-flavored treat (pup-approved)
Once-monthly ease
Beef-flavored treat (pup-approved)
Once-monthly ease
Review Summary
"Users generally praise NexGard for reliably killing fleas and ticks and for being highly palatable to dogs; a minority report gastrointestinal upset or rare neurological reactions. Overall buyers value its monthly convenience and efficacy."
Rapid flea knockdown
Afoxolaner oral chewable given once monthly to kill fleas and many tick species
Rapid flea knockdown
Afoxolaner oral chewable given once monthly to kill fleas and many tick species
Increased Safety & Security
Time-Saving Convenience
NexGard is a monthly afoxolaner oral chewable widely used for reliable flea and tick control; its large market share and competitive monthly price make it a practical core option for subscription services. Compared with longer-acting alternatives like Bravecto, NexGard’s monthly cadence yields predictable recurring revenue and simpler dose adjustments, and its narrower scope can be a lower-cost choice versus combination products that bundle heartworm or intestinal parasite protection.
Beef-flavored treat (pup-approved)
Once-monthly ease
Rapid flea knockdown
Afoxolaner oral chewable given once monthly to kill fleas and many tick species
Proven fast flea kill, typically within 24 hours of administration
Beef-flavored treat (pup-approved)
Once-monthly ease
Rapid flea knockdown
Afoxolaner oral chewable given once monthly to kill fleas and many tick species
Proven fast flea kill, typically within 24 hours of administration
$240-420 USD
Simparica Trio
Simparica Trio combines sarolaner, moxidectin and pyrantel in one monthly chewable to cover fleas, ticks, heartworm prevention and common intestinal worms, offering technical breadth that reduces the need for multiple products. For subscription buyers it often commands a premium but can deliver net savings and convenience versus purchasing separate flea and heartworm medications, distinguishing it from single-purpose chews like NexGard and Credelio.
Triple-action chew (all-in-one)
Wide parasite coverage
Triple-action chew (all-in-one)
Wide parasite coverage
Review Summary
"Simparica Trio is widely liked for its broad-spectrum protection (fleas, ticks, heartworm and intestinal parasites) and good taste, though some owners note mild GI side effects. Many users appreciate the all-in-one monthly coverage from a single chewable."
Monthly simplicity
Combines sarolaner, moxidectin and pyrantel for protection against fleas, ticks, heartworm and intestinal worms
Monthly simplicity
Combines sarolaner, moxidectin and pyrantel for protection against fleas, ticks, heartworm and intestinal worms
Increased Safety & Security
Time-Saving Convenience
Simparica Trio combines sarolaner, moxidectin and pyrantel in one monthly chewable to cover fleas, ticks, heartworm prevention and common intestinal worms, offering technical breadth that reduces the need for multiple products. For subscription buyers it often commands a premium but can deliver net savings and convenience versus purchasing separate flea and heartworm medications, distinguishing it from single-purpose chews like NexGard and Credelio.
Triple-action chew (all-in-one)
Wide parasite coverage
Monthly simplicity
Combines sarolaner, moxidectin and pyrantel for protection against fleas, ticks, heartworm and intestinal worms
Monthly chewable formulation designed for broad-spectrum parasite control
Triple-action chew (all-in-one)
Wide parasite coverage
Monthly simplicity
Combines sarolaner, moxidectin and pyrantel for protection against fleas, ticks, heartworm and intestinal worms
Monthly chewable formulation designed for broad-spectrum parasite control
$360-600 USD
Bravecto Chews
Bravecto delivers long-acting protection with a single fluralaner chew that can last up to 12 weeks against fleas and ticks, making quarterly subscriptions appealing for owners prioritizing convenience and fewer shipments. Although its per-dose cost is higher, the reduced dosing frequency can lower annual total cost and improve adherence relative to monthly chews, but it does not include heartworm or intestinal parasite coverage bundled in some monthly combination products.
12-week coverage (fewer doses)
Fast flea/tick kill
12-week coverage (fewer doses)
Fast flea/tick kill
Review Summary
"Bravecto is favored for its long-lasting (12-week) protection and convenience, with many owners reporting strong flea/tick control; however, a notable minority report occasional vomiting, lethargy, or other adverse events. Users value the reduced dosing frequency despite safety concerns from some reviewers."
Treat-like chew
Fluralaner chewable providing up to 12 weeks of protection per dose, reducing dosing frequency
Treat-like chew
Fluralaner chewable providing up to 12 weeks of protection per dose, reducing dosing frequency
Increased Safety & Security
Time-Saving Convenience
Bravecto delivers long-acting protection with a single fluralaner chew that can last up to 12 weeks against fleas and ticks, making quarterly subscriptions appealing for owners prioritizing convenience and fewer shipments. Although its per-dose cost is higher, the reduced dosing frequency can lower annual total cost and improve adherence relative to monthly chews, but it does not include heartworm or intestinal parasite coverage bundled in some monthly combination products.
12-week coverage (fewer doses)
Fast flea/tick kill
Treat-like chew
Fluralaner chewable providing up to 12 weeks of protection per dose, reducing dosing frequency
Effective against fleas and a broad range of tick species for extended intervals
12-week coverage (fewer doses)
Fast flea/tick kill
Treat-like chew
Fluralaner chewable providing up to 12 weeks of protection per dose, reducing dosing frequency
Effective against fleas and a broad range of tick species for extended intervals
$300-450 USD
Credelio
Credelio (lotilaner) is a fast-acting monthly chewable noted for rapid flea kill and reliable tick efficacy, and it is often priced competitively within subscription plans for monthly control. Like NexGard, it focuses on core flea and tick protection without integrated heartworm or deworming agents, which can keep recurring costs lower for owners who prefer to manage other preventives separately.
Fast flea kill (hours)
Small, easy chew
Fast flea kill (hours)
Small, easy chew
Review Summary
"Credelio is commonly reported as fast-acting against fleas and ticks and generally well accepted by dogs, with few side effects noted in reviews. Owners appreciate its monthly effectiveness and palatability."
Monthly routine
Lotilaner oral chewable that starts killing fleas quickly and is dosed once monthly
Monthly routine
Lotilaner oral chewable that starts killing fleas quickly and is dosed once monthly
Increased Safety & Security
Time-Saving Convenience
Credelio (lotilaner) is a fast-acting monthly chewable noted for rapid flea kill and reliable tick efficacy, and it is often priced competitively within subscription plans for monthly control. Like NexGard, it focuses on core flea and tick protection without integrated heartworm or deworming agents, which can keep recurring costs lower for owners who prefer to manage other preventives separately.
Fast flea kill (hours)
Small, easy chew
Monthly routine
Lotilaner oral chewable that starts killing fleas quickly and is dosed once monthly
Well tolerated and suitable for puppies from the approved age/weight
Fast flea kill (hours)
Small, easy chew
Monthly routine
Lotilaner oral chewable that starts killing fleas quickly and is dosed once monthly
Well tolerated and suitable for puppies from the approved age/weight
$240-360 USD
NexGard Spectra
NexGard Spectra pairs afoxolaner with milbemycin oxime to provide monthly protection against fleas, ticks, heartworms and several intestinal parasites, making it a comprehensive subscription choice for owners seeking all-in-one coverage. It competes directly with Simparica Trio on the breadth of protection but differs in active ingredients, pricing dynamics and tolerability profiles, giving subscribers an alternative comprehensive bundle to consider.
Dual-protection chew (worms + bugs)
Tasty beef bite
Dual-protection chew (worms + bugs)
Tasty beef bite
Review Summary
"NexGard Spectra receives positive feedback for combining flea/tick control with parasite protection, and dogs tend to take the chewable readily; some reviewers mention mild GI upset from the extra deworming component. Overall users find it a convenient multi-parasite monthly option."
Comprehensive monthly care
Afoxolaner plus milbemycin oxime chewable offering monthly protection against fleas, ticks, heartworm and intestinal parasites
Comprehensive monthly care
Afoxolaner plus milbemycin oxime chewable offering monthly protection against fleas, ticks, heartworm and intestinal parasites
Increased Safety & Security
Time-Saving Convenience
NexGard Spectra pairs afoxolaner with milbemycin oxime to provide monthly protection against fleas, ticks, heartworms and several intestinal parasites, making it a comprehensive subscription choice for owners seeking all-in-one coverage. It competes directly with Simparica Trio on the breadth of protection but differs in active ingredients, pricing dynamics and tolerability profiles, giving subscribers an alternative comprehensive bundle to consider.
Dual-protection chew (worms + bugs)
Tasty beef bite
Comprehensive monthly care
Afoxolaner plus milbemycin oxime chewable offering monthly protection against fleas, ticks, heartworm and intestinal parasites
Combines external and internal parasite control into a single monthly dose for convenience
Dual-protection chew (worms + bugs)
Tasty beef bite
Comprehensive monthly care
Afoxolaner plus milbemycin oxime chewable offering monthly protection against fleas, ticks, heartworm and intestinal parasites
Combines external and internal parasite control into a single monthly dose for convenience
$360-540 USD