Top 5 Vet-Backed Dog Toothpastes in the United States for 2025 — Enzymatic, Flavorful Picks to Reduce Tartar and Freshen Breath (Which One Fits Your Dog?)

Virbac's C.E.T. poultry-flavored toothpaste is the best-in-class choice for dog toothpaste because it combines a veterinary-formulated enzymatic system with high palatability, making daily brushing more effective and easier to administer than many consumer brands. It is often priced higher than mass-market options but offers stronger clinical backing and vet recommendation, so owners prioritizing measurable plaque and tartar control tend to prefer it over cheaper alternatives.

Petrodex delivers a cost-effective enzymatic dog toothpaste that balances efficacy and affordability, making it a market-leading household staple for routine oral care. Compared with premium veterinary formulas like Virbac, Petrodex is more budget-friendly and widely available in sizes and flavors, providing solid day-to-day plaque control without the higher price of clinic-grade products.

Arm & Hammer Complete Care pairs baking-soda based odor control with enzymatic action to offer an economical, dual-purpose dog toothpaste that addresses both breath and surface stains. Its household-brand recognition and focus on whitening and fresh breath make it an attractive alternative for owners seeking visible cleaning benefits at a lower price point than specialized veterinary pastes.

Nylabone's peanut-flavored toothpaste emphasizes natural ingredients and strong palatability, appealing to owners of picky or ingredient-sensitive dogs who still want routine oral hygiene. While it may lack the extensive clinical data of veterinary lines, its natural positioning and often competitive pricing make it a practical choice compared with more clinical or chemical-focused formulations.