Revolution Plus for Cats
Revolution Plus for Cats earns a top spot for its broad-spectrum protection — it addresses fleas, ticks, ear mites and several intestinal parasites while also preventing heartworm, reducing the need for multiple separate products. That technical breadth makes it more versatile than flea-only options like Advantage II or Frontline Plus, and although its per-dose price is typically higher, the consolidated coverage can be more cost-efficient for multi-threat households compared with buying several single-purpose treatments.
Broad parasite coverage
Simple monthly dose
Broad parasite coverage
Simple monthly dose
Review Summary
"Most long-term users praise Revolution Plus for reliably preventing fleas and ticks with sustained protection, though a minority report occasional mild skin or digestive reactions and note a higher price point."
Heartworm shield — tiny knight
Monthly prescription topical combining selamectin and sarolaner for broad-spectrum flea and tick control.
Heartworm shield — tiny knight
Monthly prescription topical combining selamectin and sarolaner for broad-spectrum flea and tick control.
Increased Safety & Security
Time-Saving Convenience
Revolution Plus for Cats earns a top spot for its broad-spectrum protection — it addresses fleas, ticks, ear mites and several intestinal parasites while also preventing heartworm, reducing the need for multiple separate products. That technical breadth makes it more versatile than flea-only options like Advantage II or Frontline Plus, and although its per-dose price is typically higher, the consolidated coverage can be more cost-efficient for multi-threat households compared with buying several single-purpose treatments.
Broad parasite coverage
Simple monthly dose
Heartworm shield — tiny knight
Monthly prescription topical combining selamectin and sarolaner for broad-spectrum flea and tick control.
Provides protection against fleas, several tick species and other external parasites and contributes to heartworm prevention.
Broad parasite coverage
Simple monthly dose
Heartworm shield — tiny knight
Monthly prescription topical combining selamectin and sarolaner for broad-spectrum flea and tick control.
Provides protection against fleas, several tick species and other external parasites and contributes to heartworm prevention.
$170-240 USD
Advantage II for Cats
Advantage II for Cats is a fast-acting, budget-friendly flea adulticide and larvicide that has long been popular with owners focused primarily on flea control. It does not offer the broader parasite protection of Revolution Plus or the extended dosing interval of Bravecto Plus, but its lower price point and straightforward monthly dosing make it an economical choice when fleas — rather than ticks or internal parasites — are the main concern.
Rapid flea kill
Water-resistant formula
Rapid flea kill
Water-resistant formula
Review Summary
"Users commonly report Advantage II works quickly and effectively to eliminate and prevent flea infestations, while some note it does not cover ticks and a few cats experience mild application-site irritation."
No combing needed — purrfect
Monthly topical that rapidly kills adult fleas on contact to reduce biting and irritation.
No combing needed — purrfect
Monthly topical that rapidly kills adult fleas on contact to reduce biting and irritation.
Increased Safety & Security
Time-Saving Convenience
Advantage II for Cats is a fast-acting, budget-friendly flea adulticide and larvicide that has long been popular with owners focused primarily on flea control. It does not offer the broader parasite protection of Revolution Plus or the extended dosing interval of Bravecto Plus, but its lower price point and straightforward monthly dosing make it an economical choice when fleas — rather than ticks or internal parasites — are the main concern.
Rapid flea kill
Water-resistant formula
No combing needed — purrfect
Monthly topical that rapidly kills adult fleas on contact to reduce biting and irritation.
Includes an insect growth regulator to interrupt the flea life cycle by targeting eggs and larvae.
Rapid flea kill
Water-resistant formula
No combing needed — purrfect
Monthly topical that rapidly kills adult fleas on contact to reduce biting and irritation.
Includes an insect growth regulator to interrupt the flea life cycle by targeting eggs and larvae.
$40-90 USD
Bravecto Plus for Cats
Bravecto Plus for Cats stands out for its long-duration protection: a single spot-on dose provides extended flea and tick control, which reduces the frequency of treatments and improves owner compliance. That multi-month convenience can translate into financial and logistical advantages over monthly products like Advantage II and Frontline Plus, and its strong tick efficacy is an attractive complement to broader-spectrum competitors such as Revolution Plus for owners prioritizing durable external parasite control.
Long 3-month protection
Fast tick knockdown
Long 3-month protection
Fast tick knockdown
Review Summary
"Bravecto Plus is valued for its long-lasting, low-maintenance protection and convenience, but a noticeable minority of users report side effects or inconsistent results in some cats."
Fewer doses — more play
Provides extended flea and tick control with dosing that can last up to 12 weeks per application.
Fewer doses — more play
Provides extended flea and tick control with dosing that can last up to 12 weeks per application.
Increased Safety & Security
Time-Saving Convenience
Recreational Enjoyment
Bravecto Plus for Cats stands out for its long-duration protection: a single spot-on dose provides extended flea and tick control, which reduces the frequency of treatments and improves owner compliance. That multi-month convenience can translate into financial and logistical advantages over monthly products like Advantage II and Frontline Plus, and its strong tick efficacy is an attractive complement to broader-spectrum competitors such as Revolution Plus for owners prioritizing durable external parasite control.
Long 3-month protection
Fast tick knockdown
Fewer doses — more play
Provides extended flea and tick control with dosing that can last up to 12 weeks per application.
Prescription topical offering a long residual activity to reduce the number of annual doses needed.
Long 3-month protection
Fast tick knockdown
Fewer doses — more play
Provides extended flea and tick control with dosing that can last up to 12 weeks per application.
Prescription topical offering a long residual activity to reduce the number of annual doses needed.
$100-180 USD
Catego for Cats
Catego for Cats is positioned as a value-oriented, EU-sourced spot-on that emphasizes rapid flea knockdown and suitability for multi-cat households, offering an accessible alternative to legacy brands. While it generally does not claim the same breadth of internal parasite coverage as Revolution Plus or the multi-month label of Bravecto Plus, Catego can be a cost-effective option for owners seeking straightforward flea and tick control without premium pricing.
Powerful ectoparasite control
Monthly spot-on ease
Powerful ectoparasite control
Monthly spot-on ease
Review Summary
"Catego gets mixed reviews: some owners report good flea control and value, while others cite inconsistent effectiveness, availability challenges, or occasional skin sensitivity in their cats."
Science-backed formula — ninja fleas beware
Over-the-counter spot-on option commonly sold in American retailers for routine flea management.
Science-backed formula — ninja fleas beware
Over-the-counter spot-on option commonly sold in American retailers for routine flea management.
Increased Safety & Security
Time-Saving Convenience
Catego for Cats is positioned as a value-oriented, EU-sourced spot-on that emphasizes rapid flea knockdown and suitability for multi-cat households, offering an accessible alternative to legacy brands. While it generally does not claim the same breadth of internal parasite coverage as Revolution Plus or the multi-month label of Bravecto Plus, Catego can be a cost-effective option for owners seeking straightforward flea and tick control without premium pricing.
Powerful ectoparasite control
Monthly spot-on ease
Science-backed formula — ninja fleas beware
Over-the-counter spot-on option commonly sold in American retailers for routine flea management.
Formulated to kill adult fleas while helping reduce immature stages to lower household infestation pressure.
Powerful ectoparasite control
Monthly spot-on ease
Science-backed formula — ninja fleas beware
Over-the-counter spot-on option commonly sold in American retailers for routine flea management.
Formulated to kill adult fleas while helping reduce immature stages to lower household infestation pressure.
$35-80 USD
Frontline Plus for Cats
Frontline Plus for Cats is a long-standing market leader known for consistent efficacy against fleas and ticks, wide retail availability, and strong consumer recognition. It provides reliable month-to-month control similar to Advantage II but does not treat internal parasites like Revolution Plus or offer the extended dosing interval of Bravecto Plus; its ubiquity and steady performance make it a low-risk, competitively priced choice for many cat owners.
Dual-action formula
Proven long-standing brand
Dual-action formula
Proven long-standing brand
Review Summary
"Frontline Plus is widely liked for dependable flea and tick control and easy application, though some owners report reduced effectiveness in heavy infestations and occasional local skin reactions."
Oil-based spread — cape for cats
Monthly topical with fipronil and (S)-methoprene that kills adult fleas, ticks and flea eggs/larvae.
Oil-based spread — cape for cats
Monthly topical with fipronil and (S)-methoprene that kills adult fleas, ticks and flea eggs/larvae.
Increased Safety & Security
Time-Saving Convenience
Frontline Plus for Cats is a long-standing market leader known for consistent efficacy against fleas and ticks, wide retail availability, and strong consumer recognition. It provides reliable month-to-month control similar to Advantage II but does not treat internal parasites like Revolution Plus or offer the extended dosing interval of Bravecto Plus; its ubiquity and steady performance make it a low-risk, competitively priced choice for many cat owners.
Dual-action formula
Proven long-standing brand
Oil-based spread — cape for cats
Monthly topical with fipronil and (S)-methoprene that kills adult fleas, ticks and flea eggs/larvae.
Longstanding, widely stocked product at veterinary clinics and retailers across the USA.
Dual-action formula
Proven long-standing brand
Oil-based spread — cape for cats
Monthly topical with fipronil and (S)-methoprene that kills adult fleas, ticks and flea eggs/larvae.
Longstanding, widely stocked product at veterinary clinics and retailers across the USA.
$50-120 USD