Panacur Granules (fenbendazole) are a flexible, economical oral broad-spectrum treatment prized for adaptable dosing and proven efficacy against a wide range of intestinal parasites, including some protozoal infections where others are less effective. While less convenient than tablets or chews for routine monthly prevention, Panacur’s financial and technical advantages show in bulk or targeted treatment scenarios—kennel use, multi-dose regimens, and hard-to-eradicate infections—making it an important tool alongside the more user-friendly options listed above.
Sprinkle-on dosing
Giardia buster
Sprinkle-on dosing
Giardia buster
Review Summary
"Panacur granules (fenbendazole) are widely rated as very effective, particularly for Giardia and common intestinal parasites, and are well tolerated even with multi-day regimens; taste can be an issue so owners often mix with food. Many reviewers highlight its safety and versatility across species."
Flexible multi-day
Contains fenbendazole, effective against many gastrointestinal nematodes and certain protozoa such as Giardia.
Flexible multi-day
Contains fenbendazole, effective against many gastrointestinal nematodes and certain protozoa such as Giardia.
Increased Safety & Security
Time-Saving Convenience
Panacur Granules (fenbendazole) are a flexible, economical oral broad-spectrum treatment prized for adaptable dosing and proven efficacy against a wide range of intestinal parasites, including some protozoal infections where others are less effective. While less convenient than tablets or chews for routine monthly prevention, Panacur’s financial and technical advantages show in bulk or targeted treatment scenarios—kennel use, multi-dose regimens, and hard-to-eradicate infections—making it an important tool alongside the more user-friendly options listed above.
Sprinkle-on dosing
Giardia buster
Flexible multi-day
Contains fenbendazole, effective against many gastrointestinal nematodes and certain protozoa such as Giardia.
Granule form allows flexible dosing for dogs, cats and some exotic species.
Sprinkle-on dosing
Giardia buster
Flexible multi-day
Contains fenbendazole, effective against many gastrointestinal nematodes and certain protozoa such as Giardia.
Granule form allows flexible dosing for dogs, cats and some exotic species.
$20-50 USD
Revolution Plus for Cats
Revolution Plus for Cats earns a top spot for its broad-spectrum protection — it addresses fleas, ticks, ear mites and several intestinal parasites while also preventing heartworm, reducing the need for multiple separate products. That technical breadth makes it more versatile than flea-only options like Advantage II or Frontline Plus, and although its per-dose price is typically higher, the consolidated coverage can be more cost-efficient for multi-threat households compared with buying several single-purpose treatments.
Broad parasite coverage
Simple monthly dose
Broad parasite coverage
Simple monthly dose
Review Summary
"Most long-term users praise Revolution Plus for reliably preventing fleas and ticks with sustained protection, though a minority report occasional mild skin or digestive reactions and note a higher price point."
Heartworm shield — tiny knight
Monthly prescription topical combining selamectin and sarolaner for broad-spectrum flea and tick control.
Heartworm shield — tiny knight
Monthly prescription topical combining selamectin and sarolaner for broad-spectrum flea and tick control.
Increased Safety & Security
Time-Saving Convenience
Revolution Plus for Cats earns a top spot for its broad-spectrum protection — it addresses fleas, ticks, ear mites and several intestinal parasites while also preventing heartworm, reducing the need for multiple separate products. That technical breadth makes it more versatile than flea-only options like Advantage II or Frontline Plus, and although its per-dose price is typically higher, the consolidated coverage can be more cost-efficient for multi-threat households compared with buying several single-purpose treatments.
Broad parasite coverage
Simple monthly dose
Heartworm shield — tiny knight
Monthly prescription topical combining selamectin and sarolaner for broad-spectrum flea and tick control.
Provides protection against fleas, several tick species and other external parasites and contributes to heartworm prevention.
Broad parasite coverage
Simple monthly dose
Heartworm shield — tiny knight
Monthly prescription topical combining selamectin and sarolaner for broad-spectrum flea and tick control.
Provides protection against fleas, several tick species and other external parasites and contributes to heartworm prevention.
$170-240 USD
Drontal Plus is a best-in-class broad‑spectrum oral tablet that combines praziquantel with complementary anthelmintics to reliably clear tapeworms while also treating roundworms and hookworms. Its strong value proposition is cost‑effective multi‑parasite control in a single, palatable dose, making it a practical alternative to pricier single‑purpose tapeworm products when mixed infections are a concern compared with more narrowly targeted options on this list.
Broad-spectrum action
One-pill solution
Broad-spectrum action
One-pill solution
Review Summary
"Users report Drontal Plus reliably clears tapeworms and other common intestinal parasites with fast results; tablets are generally well tolerated though a few owners note mild vomiting or difficulty getting dogs to take pills."
Meat-flavored mischief
Chewable tablets combining praziquantel, febantel and pyrantel to treat tapeworms, roundworms and hookworms.
Meat-flavored mischief
Chewable tablets combining praziquantel, febantel and pyrantel to treat tapeworms, roundworms and hookworms.
Increased Safety & Security
Time-Saving Convenience
Drontal Plus is a best-in-class broad‑spectrum oral tablet that combines praziquantel with complementary anthelmintics to reliably clear tapeworms while also treating roundworms and hookworms. Its strong value proposition is cost‑effective multi‑parasite control in a single, palatable dose, making it a practical alternative to pricier single‑purpose tapeworm products when mixed infections are a concern compared with more narrowly targeted options on this list.
Broad-spectrum action
One-pill solution
Meat-flavored mischief
Chewable tablets combining praziquantel, febantel and pyrantel to treat tapeworms, roundworms and hookworms.
Formulated for a range of dog sizes with weight-based dosing for single-visit deworming.
Broad-spectrum action
One-pill solution
Meat-flavored mischief
Chewable tablets combining praziquantel, febantel and pyrantel to treat tapeworms, roundworms and hookworms.
Formulated for a range of dog sizes with weight-based dosing for single-visit deworming.
$30-80 USD
Interceptor (milbemycin oxime) is a straightforward, well-tolerated oral heartworm preventive that also covers several intestinal nematodes; its simplicity and low per-dose cost make it a practical backbone product for routine heartworm control. Financially it is often less expensive than combination topical options and is especially attractive for multi-cat households or programs where an oral tablet is preferred over topicals like Revolution Plus or Bravecto Plus.
Palatable tablet
Monthly oral ease
Palatable tablet
Monthly oral ease
Review Summary
"Interceptor receives consistent praise for dependable monthly heartworm and worm prevention and ease of administration, with palatability sometimes an issue for finicky cats."
Worm-targeted focus
Monthly oral chewable (milbemycin oxime) that prevents heartworm disease and treats common intestinal nematodes.
Worm-targeted focus
Monthly oral chewable (milbemycin oxime) that prevents heartworm disease and treats common intestinal nematodes.
Increased Safety & Security
Time-Saving Convenience
Interceptor (milbemycin oxime) is a straightforward, well-tolerated oral heartworm preventive that also covers several intestinal nematodes; its simplicity and low per-dose cost make it a practical backbone product for routine heartworm control. Financially it is often less expensive than combination topical options and is especially attractive for multi-cat households or programs where an oral tablet is preferred over topicals like Revolution Plus or Bravecto Plus.
Palatable tablet
Monthly oral ease
Worm-targeted focus
Monthly oral chewable (milbemycin oxime) that prevents heartworm disease and treats common intestinal nematodes.
Well-suited for owners who prefer a pill rather than a topical application for regular heartworm prevention.
Palatable tablet
Monthly oral ease
Worm-targeted focus
Monthly oral chewable (milbemycin oxime) that prevents heartworm disease and treats common intestinal nematodes.
Well-suited for owners who prefer a pill rather than a topical application for regular heartworm prevention.
$100-180 USD
Nemex-2 Liquid Dewormer
Nemex‑2 Liquid Dewormer (fenbendazole) is valued for its broad nematode coverage and utility in multi‑day treatment courses, making it especially useful for whipworms and certain roundworm infections where a longer regimen is advised. Financially it sits between single‑ingredient pyrantel products and premium combination brands like Drontal, and technically it offers an advantage for cases needing repeat dosing or broader nematode efficacy compared to pyrantel alone.
Trusted pyrantel formula
Liquid for easy dosing
Trusted pyrantel formula
Liquid for easy dosing
Review Summary
"Nemex-2 liquid is commonly reported as effective and easy to administer for kittens and young cats, consistently clearing roundworms for most users though some recommend repeat dosing or vet confirmation."
Soothing flavor hint
Pyrantel-based liquid designed specifically for safe use in young kittens
Soothing flavor hint
Pyrantel-based liquid designed specifically for safe use in young kittens
Increased Safety & Security
Nemex‑2 Liquid Dewormer (fenbendazole) is valued for its broad nematode coverage and utility in multi‑day treatment courses, making it especially useful for whipworms and certain roundworm infections where a longer regimen is advised. Financially it sits between single‑ingredient pyrantel products and premium combination brands like Drontal, and technically it offers an advantage for cases needing repeat dosing or broader nematode efficacy compared to pyrantel alone.
Trusted pyrantel formula
Liquid for easy dosing
Soothing flavor hint
Pyrantel-based liquid designed specifically for safe use in young kittens
Simple weight-based dosing makes it straightforward for multi-pet households
Trusted pyrantel formula
Liquid for easy dosing
Soothing flavor hint
Pyrantel-based liquid designed specifically for safe use in young kittens
Simple weight-based dosing makes it straightforward for multi-pet households
$12-28 USD
Interceptor Plus Complete Parasite Protocol
Interceptor Plus is the market leader for integrated parasite protocols because it combines monthly heartworm prevention with broad-spectrum intestinal parasite control in a single chewable, reducing the need for separate products in clinic-prescribed regimens. While its consolidated protection can come at a higher per-dose price versus single-purpose dewormers, that financial trade-off is often justified by the simplified protocol and reduced risk of missed indications (e.g., heartworm) compared with other entries on this list.
Heartworm bodyguard
Monthly chewable shield
Heartworm bodyguard
Monthly chewable shield
Review Summary
"Pet owners like Interceptor Plus as a once-monthly chewable that provides broad protection (heartworm and intestinal parasites) with high efficacy and good palatability; rare adverse reactions are reported."
Multi-parasite control
Monthly oral chewable combining milbemycin oxime and praziquantel to prevent heartworm and treat intestinal parasites including tapeworms.
Multi-parasite control
Monthly oral chewable combining milbemycin oxime and praziquantel to prevent heartworm and treat intestinal parasites including tapeworms.
Increased Safety & Security
Time-Saving Convenience
Interceptor Plus is the market leader for integrated parasite protocols because it combines monthly heartworm prevention with broad-spectrum intestinal parasite control in a single chewable, reducing the need for separate products in clinic-prescribed regimens. While its consolidated protection can come at a higher per-dose price versus single-purpose dewormers, that financial trade-off is often justified by the simplified protocol and reduced risk of missed indications (e.g., heartworm) compared with other entries on this list.
Heartworm bodyguard
Monthly chewable shield
Multi-parasite control
Monthly oral chewable combining milbemycin oxime and praziquantel to prevent heartworm and treat intestinal parasites including tapeworms.
Palatable monthly dosing improves owner compliance for year-round parasite control.
Heartworm bodyguard
Monthly chewable shield
Multi-parasite control
Monthly oral chewable combining milbemycin oxime and praziquantel to prevent heartworm and treat intestinal parasites including tapeworms.
Palatable monthly dosing improves owner compliance for year-round parasite control.
$120-300 USD