Revolution Plus for Cats
Revolution Plus (selamectin + sarolaner) is a monthly topical that leads the list by combining reliable heartworm prevention with broad-spectrum flea and tick control, reducing the need to buy separate tick products. Its technical advantage is the single topical combination that covers both endo- and ectoparasites, which can translate to lower overall annual cost and simpler compliance compared with products that require additional medications like standalone oral heartworm pills or separate tick treatments.
Broad parasite coverage
Monthly spot-on
Broad parasite coverage
Monthly spot-on
Review Summary
"Owners praise Revolution Plus for its broad-spectrum, once-monthly topical protection and find it effective and easy to use, with only rare reports of mild skin or GI reactions."
Salmon-scent wink
Monthly topical (selamectin + sarolaner) that prevents heartworm disease and treats fleas, ticks, ear mites and many intestinal parasites.
Salmon-scent wink
Monthly topical (selamectin + sarolaner) that prevents heartworm disease and treats fleas, ticks, ear mites and many intestinal parasites.
Increased Safety & Security
Time-Saving Convenience
Revolution Plus (selamectin + sarolaner) is a monthly topical that leads the list by combining reliable heartworm prevention with broad-spectrum flea and tick control, reducing the need to buy separate tick products. Its technical advantage is the single topical combination that covers both endo- and ectoparasites, which can translate to lower overall annual cost and simpler compliance compared with products that require additional medications like standalone oral heartworm pills or separate tick treatments.
Broad parasite coverage
Monthly spot-on
Salmon-scent wink
Monthly topical (selamectin + sarolaner) that prevents heartworm disease and treats fleas, ticks, ear mites and many intestinal parasites.
Broad-spectrum protection including flea control and tick prevention alongside heartworm prophylaxis.
Broad parasite coverage
Monthly spot-on
Salmon-scent wink
Monthly topical (selamectin + sarolaner) that prevents heartworm disease and treats fleas, ticks, ear mites and many intestinal parasites.
Broad-spectrum protection including flea control and tick prevention alongside heartworm prophylaxis.
$200-300 USD
Advantage Multi for Cats
Advantage Multi (imidacloprid + moxidectin) is a long-established monthly topical that delivers consistent heartworm prevention along with activity against common intestinal parasites, making it a cost-effective, clinic-familiar choice. Compared with newer combination brands, its financial advantage is often competitive pricing and a proven safety and efficacy record, which can yield better margins for clinics while still meeting core heartworm prevention needs.
Dual-action protection
Topical monthly ease
Dual-action protection
Topical monthly ease
Review Summary
"Users report Advantage Multi reliably prevents heartworm and many intestinal parasites and is straightforward to apply, though a minority mention application-site mess or occasional mild GI upset."
Waterproof after dry
Monthly topical (imidacloprid + moxidectin) proven for heartworm prevention and effective against fleas and several intestinal worms.
Waterproof after dry
Monthly topical (imidacloprid + moxidectin) proven for heartworm prevention and effective against fleas and several intestinal worms.
Increased Safety & Security
Time-Saving Convenience
Advantage Multi (imidacloprid + moxidectin) is a long-established monthly topical that delivers consistent heartworm prevention along with activity against common intestinal parasites, making it a cost-effective, clinic-familiar choice. Compared with newer combination brands, its financial advantage is often competitive pricing and a proven safety and efficacy record, which can yield better margins for clinics while still meeting core heartworm prevention needs.
Dual-action protection
Topical monthly ease
Waterproof after dry
Monthly topical (imidacloprid + moxidectin) proven for heartworm prevention and effective against fleas and several intestinal worms.
Good choice for cats needing combined flea control and heartworm prophylaxis in one monthly dose.
Dual-action protection
Topical monthly ease
Waterproof after dry
Monthly topical (imidacloprid + moxidectin) proven for heartworm prevention and effective against fleas and several intestinal worms.
Good choice for cats needing combined flea control and heartworm prophylaxis in one monthly dose.
$160-240 USD
Bravecto Plus for Cats
Bravecto Plus (fluralaner + moxidectin) differentiates itself by pairing extended-duration flea and tick protection with moxidectin-based heartworm prevention, cutting dosing frequency and improving owner compliance. Although each dose is typically more expensive than monthly options, the technical benefit of longer intervals can reduce missed doses and overall long-term cost for owners who prefer less frequent administration compared with monthly products like Revolution Plus or Advantage Multi.
Quarterly protection
Spot-on convenience
Quarterly protection
Spot-on convenience
Review Summary
"Bravecto Plus is valued for long-lasting flea and tick control and convenient dosing intervals, but some owners note higher cost and occasional adverse reactions in sensitive cats."
Cat-approved naps
Longer-acting chewable/topical (fluralaner-based) formulation that offers extended flea and tick control with added heartworm-active ingredient.
Cat-approved naps
Longer-acting chewable/topical (fluralaner-based) formulation that offers extended flea and tick control with added heartworm-active ingredient.
Increased Safety & Security
Time-Saving Convenience
Bravecto Plus (fluralaner + moxidectin) differentiates itself by pairing extended-duration flea and tick protection with moxidectin-based heartworm prevention, cutting dosing frequency and improving owner compliance. Although each dose is typically more expensive than monthly options, the technical benefit of longer intervals can reduce missed doses and overall long-term cost for owners who prefer less frequent administration compared with monthly products like Revolution Plus or Advantage Multi.
Quarterly protection
Spot-on convenience
Cat-approved naps
Longer-acting chewable/topical (fluralaner-based) formulation that offers extended flea and tick control with added heartworm-active ingredient.
Doses spaced farther apart for owners preferring less frequent administration while maintaining heartworm protection.
Quarterly protection
Spot-on convenience
Cat-approved naps
Longer-acting chewable/topical (fluralaner-based) formulation that offers extended flea and tick control with added heartworm-active ingredient.
Doses spaced farther apart for owners preferring less frequent administration while maintaining heartworm protection.
$130-240 USD
Interceptor for Cats
Interceptor (milbemycin oxime) is a straightforward, well-tolerated oral heartworm preventive that also covers several intestinal nematodes; its simplicity and low per-dose cost make it a practical backbone product for routine heartworm control. Financially it is often less expensive than combination topical options and is especially attractive for multi-cat households or programs where an oral tablet is preferred over topicals like Revolution Plus or Bravecto Plus.
Palatable tablet
Monthly oral ease
Palatable tablet
Monthly oral ease
Review Summary
"Interceptor receives consistent praise for dependable monthly heartworm and worm prevention and ease of administration, with palatability sometimes an issue for finicky cats."
Worm-targeted focus
Monthly oral chewable (milbemycin oxime) that prevents heartworm disease and treats common intestinal nematodes.
Worm-targeted focus
Monthly oral chewable (milbemycin oxime) that prevents heartworm disease and treats common intestinal nematodes.
Increased Safety & Security
Time-Saving Convenience
Interceptor (milbemycin oxime) is a straightforward, well-tolerated oral heartworm preventive that also covers several intestinal nematodes; its simplicity and low per-dose cost make it a practical backbone product for routine heartworm control. Financially it is often less expensive than combination topical options and is especially attractive for multi-cat households or programs where an oral tablet is preferred over topicals like Revolution Plus or Bravecto Plus.
Palatable tablet
Monthly oral ease
Worm-targeted focus
Monthly oral chewable (milbemycin oxime) that prevents heartworm disease and treats common intestinal nematodes.
Well-suited for owners who prefer a pill rather than a topical application for regular heartworm prevention.
Palatable tablet
Monthly oral ease
Worm-targeted focus
Monthly oral chewable (milbemycin oxime) that prevents heartworm disease and treats common intestinal nematodes.
Well-suited for owners who prefer a pill rather than a topical application for regular heartworm prevention.
$100-180 USD
Milbemax for Cats
Milbemax (milbemycin oxime + praziquantel) offers oral heartworm prevention together with reliable tapeworm treatment, providing an efficient all-in-one solution for owners needing cestode coverage as well as nematode and heartworm control. Compared with Interceptor, Milbemax’s added praziquantel can remove the need for a separate tapeworm product, which may lower total treatment costs and simplify parasite control plans for cats with mixed infections.
Broad worm coverage
Tiny flavored tablet
Broad worm coverage
Tiny flavored tablet
Review Summary
"Milbemax is commonly rated effective for treating tapeworms and other intestinal parasites with predictable results, though a small number of users report transient gastrointestinal upset."
Fast tapeworm zap
Monthly tablet combining milbemycin oxime and praziquantel to prevent heartworm and treat tapeworms.
Fast tapeworm zap
Monthly tablet combining milbemycin oxime and praziquantel to prevent heartworm and treat tapeworms.
Increased Safety & Security
Time-Saving Convenience
Milbemax (milbemycin oxime + praziquantel) offers oral heartworm prevention together with reliable tapeworm treatment, providing an efficient all-in-one solution for owners needing cestode coverage as well as nematode and heartworm control. Compared with Interceptor, Milbemax’s added praziquantel can remove the need for a separate tapeworm product, which may lower total treatment costs and simplify parasite control plans for cats with mixed infections.
Broad worm coverage
Tiny flavored tablet
Fast tapeworm zap
Monthly tablet combining milbemycin oxime and praziquantel to prevent heartworm and treat tapeworms.
Compact, oral formulation useful for simultaneous heartworm prophylaxis and tapeworm control.
Broad worm coverage
Tiny flavored tablet
Fast tapeworm zap
Monthly tablet combining milbemycin oxime and praziquantel to prevent heartworm and treat tapeworms.
Compact, oral formulation useful for simultaneous heartworm prophylaxis and tapeworm control.
$80-140 USD