Caninsulin VetPen is a veterinary-formulated porcine insulin zinc suspension offered in a pen format that simplifies dosing for dogs and reduces wastage compared with vial-only products. It is positioned as a cost-conscious, clinic-friendly option with dosing pens that improve owner compliance versus vial-based insulins like Prozinc, while providing a more veterinary-focused formulation than human products such as Lantus or Humulin N.
Prefilled pen
Vet-formulated
Prefilled pen
Vet-formulated
Review Summary
"Owners frequently praise Caninsulin VetPen for easy dosing and generally reliable glycemic control in dogs, though some report occasional supply issues or variability between batches. The pen format and veterinary focus are cited as major advantages for long‑term use."
Tail-approved ease
Porcine zinc insulin formulated specifically for dogs and licensed for veterinary use.
Tail-approved ease
Porcine zinc insulin formulated specifically for dogs and licensed for veterinary use.
Increased Safety & Security
Time-Saving Convenience
Skill Development & Mastery
Caninsulin VetPen is a veterinary-formulated porcine insulin zinc suspension offered in a pen format that simplifies dosing for dogs and reduces wastage compared with vial-only products. It is positioned as a cost-conscious, clinic-friendly option with dosing pens that improve owner compliance versus vial-based insulins like Prozinc, while providing a more veterinary-focused formulation than human products such as Lantus or Humulin N.
Prefilled pen
Vet-formulated
Tail-approved ease
Porcine zinc insulin formulated specifically for dogs and licensed for veterinary use.
Available as a prefilled VetPen option for more precise dosing and easier owner administration.
Prefilled pen
Vet-formulated
Tail-approved ease
Porcine zinc insulin formulated specifically for dogs and licensed for veterinary use.
Available as a prefilled VetPen option for more precise dosing and easier owner administration.
$150-260 USD
Vetsulin (Caninsulin)
Vetsulin (marketed as Caninsulin in some regions) is a veterinary porcine insulin zinc suspension widely regarded as the market-leading insulin therapy for canine diabetes because of its established clinical track record and predictable glycemic control. Although it is an injectable product rather than an oral regulator, its technical advantage is robust efficacy where oral agents often fail, making it the go-to choice for dogs requiring definitive insulin replacement. Financially, Vetsulin's pricing reflects its regulatory approvals and manufacturer support, which can be higher than compounded oral options but is justified by superior clinical consistency and product reliability.
Fast glucose control - tail-approved
Dog-specific insulin formula
Fast glucose control - tail-approved
Dog-specific insulin formula
Review Summary
"Users generally report reliable glycemic control with Vetsulin/Caninsulin when dosed and handled properly; some cite variability between batches and occasional dosing challenges but overall steady improvement in diabetic dogs."
Vet-prescribed reliability
Porcine lente insulin (Vetsulin/Caninsulin) formulated specifically for dogs and cats.
Vet-prescribed reliability
Porcine lente insulin (Vetsulin/Caninsulin) formulated specifically for dogs and cats.
Increased Safety & Security
Skill Development & Mastery
Vetsulin (marketed as Caninsulin in some regions) is a veterinary porcine insulin zinc suspension widely regarded as the market-leading insulin therapy for canine diabetes because of its established clinical track record and predictable glycemic control. Although it is an injectable product rather than an oral regulator, its technical advantage is robust efficacy where oral agents often fail, making it the go-to choice for dogs requiring definitive insulin replacement. Financially, Vetsulin's pricing reflects its regulatory approvals and manufacturer support, which can be higher than compounded oral options but is justified by superior clinical consistency and product reliability.
Fast glucose control - tail-approved
Dog-specific insulin formula
Vet-prescribed reliability
Porcine lente insulin (Vetsulin/Caninsulin) formulated specifically for dogs and cats.
Typically administered by subcutaneous injection, often twice daily with dose titration based on glucose curves.
Fast glucose control - tail-approved
Dog-specific insulin formula
Vet-prescribed reliability
Porcine lente insulin (Vetsulin/Caninsulin) formulated specifically for dogs and cats.
Typically administered by subcutaneous injection, often twice daily with dose titration based on glucose curves.
$90-150 USD
Thyrosyn occupies a niche in the veterinary thyroid replacement market by offering formulations and tablet sizes intended for small-breed or sensitive canine patients where fine-tuned dosing is required. It is often chosen when clinicians need more tailored dosing than standard tablets provide; however, that specificity can come with higher per-dose costs compared with mass-market options such as Soloxine or generic levothyroxine tablets.
Flexible dosing
Economy option
Flexible dosing
Economy option
Review Summary
"Thyrosyn receives mixed-to-positive feedback: many owners see good symptom control and improved quality of life, while others experience variable response or require frequent blood testing and dose adjustments. Reviews indicate good efficacy for some dogs but less consistency across the board."
Reliable supply
Formulation provides liothyronine (T3) for more rapid onset in selected or refractory cases (used less commonly than T4).
Reliable supply
Formulation provides liothyronine (T3) for more rapid onset in selected or refractory cases (used less commonly than T4).
Increased Safety & Security
Time-Saving Convenience
Thyrosyn occupies a niche in the veterinary thyroid replacement market by offering formulations and tablet sizes intended for small-breed or sensitive canine patients where fine-tuned dosing is required. It is often chosen when clinicians need more tailored dosing than standard tablets provide; however, that specificity can come with higher per-dose costs compared with mass-market options such as Soloxine or generic levothyroxine tablets.
Flexible dosing
Economy option
Reliable supply
Formulation provides liothyronine (T3) for more rapid onset in selected or refractory cases (used less commonly than T4).
Typically reserved for short-term use or specialist-managed combination therapy alongside T4 under veterinary oversight.
Flexible dosing
Economy option
Reliable supply
Formulation provides liothyronine (T3) for more rapid onset in selected or refractory cases (used less commonly than T4).
Typically reserved for short-term use or specialist-managed combination therapy alongside T4 under veterinary oversight.
$60-200 USD
Percorten-V Injectable
Percorten‑V (desoxycorticosterone pivalate, DOCP) Injectable is the market‑leading long‑acting parenteral mineralocorticoid for dogs with primary hypoadrenocorticism, delivering predictable monthly electrolyte control. Its technical advantage over oral Florinef is steadier mineralocorticoid replacement with fewer compliance issues and often better long‑term cost‑effectiveness despite higher upfront injection visit charges; because it lacks glucocorticoid activity it is routinely used alongside a separate glucocorticoid such as prednisolone.
Long-acting injection
Fewer daily pills
Long-acting injection
Fewer daily pills
Review Summary
"Percorten-V is widely praised for consistent, long-lasting mineralocorticoid replacement and predictable monthly control; main complaints are expense and the necessity of veterinary-administered injections."
Bounce-back energy
Monthly injectable desoxycorticosterone pivalate for reliable mineralocorticoid replacement.
Bounce-back energy
Monthly injectable desoxycorticosterone pivalate for reliable mineralocorticoid replacement.
Increased Safety & Security
Time-Saving Convenience
Percorten‑V (desoxycorticosterone pivalate, DOCP) Injectable is the market‑leading long‑acting parenteral mineralocorticoid for dogs with primary hypoadrenocorticism, delivering predictable monthly electrolyte control. Its technical advantage over oral Florinef is steadier mineralocorticoid replacement with fewer compliance issues and often better long‑term cost‑effectiveness despite higher upfront injection visit charges; because it lacks glucocorticoid activity it is routinely used alongside a separate glucocorticoid such as prednisolone.
Long-acting injection
Fewer daily pills
Bounce-back energy
Monthly injectable desoxycorticosterone pivalate for reliable mineralocorticoid replacement.
Provides consistent electrolyte control with less frequent dosing than oral options.
Long-acting injection
Fewer daily pills
Bounce-back energy
Monthly injectable desoxycorticosterone pivalate for reliable mineralocorticoid replacement.
Provides consistent electrolyte control with less frequent dosing than oral options.
$120-250 USD
DDAVP Desmopressin Acetate Tablets
DDAVP is the go-to ADH replacement for canine central diabetes insipidus because it provides a highly specific vasopressin analog in an easy-to-dose oral tablet, enabling reliable control of polyuria/polydipsia with minimal systemic steroid or adrenal effects. Compared with adrenal-directed therapies on this list (trilostane, mitotane, DOCP), DDAVP targets the neurohypophyseal axis directly and usually delivers lower monitoring intensity and lower ongoing lab costs, making it a cost-efficient chronic option for ADH-deficient patients.
Controls urination
Prevents dehydration
Controls urination
Prevents dehydration
Review Summary
"Owners report a significant reduction in excessive drinking and urination with DDAVP tablets and improved quality of life; some note the need for dosing adjustments, cost concerns, or occasional variable response."
Pocket-tablet hero
Synthetic vasopressin analogue used to replace ADH in central diabetes insipidus.
Pocket-tablet hero
Synthetic vasopressin analogue used to replace ADH in central diabetes insipidus.
Increased Safety & Security
Time-Saving Convenience
DDAVP is the go-to ADH replacement for canine central diabetes insipidus because it provides a highly specific vasopressin analog in an easy-to-dose oral tablet, enabling reliable control of polyuria/polydipsia with minimal systemic steroid or adrenal effects. Compared with adrenal-directed therapies on this list (trilostane, mitotane, DOCP), DDAVP targets the neurohypophyseal axis directly and usually delivers lower monitoring intensity and lower ongoing lab costs, making it a cost-efficient chronic option for ADH-deficient patients.
Controls urination
Prevents dehydration
Pocket-tablet hero
Synthetic vasopressin analogue used to replace ADH in central diabetes insipidus.
Oral tablet formulation that is typically dosed multiple times daily with dose titration based on water intake and urine concentration.
Controls urination
Prevents dehydration
Pocket-tablet hero
Synthetic vasopressin analogue used to replace ADH in central diabetes insipidus.
Oral tablet formulation that is typically dosed multiple times daily with dose titration based on water intake and urine concentration.
$40-120 USD